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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Tau phosphorylation regulates the interaction between BIN1’s SH3 domain and Tau’s proline-rich domain

Fig. 4

BIN1-Tau complexes are rarely co-localized with clathrin-coated membranes and are not co-localized with synaptic markers. a. A PLA for Tau-BIN1 (green) and clathrin staining (red) in primary neuron cultures. b. A PLA for Tau-BIN1 (green) and the pre-synaptic marker synaptophysin (red) in primary neuron cultures. c. A PLA for Tau-BIN1 (green) and the post-synaptic marker PSD95 (red) in primary neuron cultures. Upper panels: maximum intensity projection. Lower panels: a single confocal Z-stack. Mag: magnification

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