Fig. 2

Photomicrographs of paraffin-embedded sections of spinal cord and primary sensory neurons. a Sacral dorsal horn of a subject with dementia with Lewy bodies containing numerous LBAS deposits. b–e Lewy neurites (b), neuronal cytoplasmic diffuse granular appearance (c), and intraneuronal cytoplasmic bodies (d, e) in the dorsal root ganglia of subjects with dementia with Lewy bodies. f Lewy body in the dorsal root ganglia of a subject with Parkinson’s disease. g Proximal portion of the cervical dorsal root showing a swollen neurite (arrow). h–j LBAS in large motor neurons of the ventral horn of subjects with dementia with Lewy bodies. Neuronal cytoplasmic diffuse granular appearance (h, i) and intraneuronal cytoplasmic body (j). Phosphorylated α-synuclein immunohistochemical staining (a–e, g–j) or hematoxylin and eosin (f). scale bar = 100 μm for (a, g); 20 μm for (b–f, h–j). LBAS, Lewy body–related α-synucleinopathy