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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Distribution of α-synuclein in the spinal cord and dorsal root ganglia in an autopsy cohort of elderly persons

Fig. 1

Correlation between LBAS density in specific regions of the brain and in the S2 dorsal horn. Correlation between LBAS density in the medullary reticular formation (a), locus ceruleus (b), or amygdala (c) and in the S2 dorsal horn. Each symbol represents one subject. A density score of 1 or more indicates the deposition of LBAS, with increasing density score indicating greater deposition. Correlation was assessed by calculating Spearman’s rank correlation coefficient. c Most subjects with LBAS in the medullary reticular formation or locus ceruleus (open circles) had LBAS in the S2 dorsal horn (S2 dorsal horn density score ≥1). Even when the amygdala showed a higher degree of LBAS (density score 3 or 4), subjects who lacked LBAS in the medullary reticular formation and locus ceruleus (closed triangles) failed to show LBAS in the S2 dorsal horn (S2 dorsal horn density score = 0). LBAS, Lewy body–related α-synucleinopathy

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