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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse

Fig. 5

Stereological assessments of brain pathology and integrity. Representative images of microglial (CD68; a + b), phosphorylated-tau (c + d), TDP-43 (e + f), ubiquitin (g + h) and α-synuclein (i + j) staining in the hippocampus (CA1) from LBC1936 (a, c, e ,g, i) and AD (b, d, f, h, j) brains. Large scale bar = 50 μm, insert scale bars = 10 μm. k Histogram showing neuronal densities in eight cortical regions from the LBC1936 (black bars) and AD (grey bars) brains. l Histogram showing microglial densities (CD68-positive cells) in eight cortical regions from the LBC1936 and AD brains. m Histogram of cortical thickness measurements from eight cortical regions in the LBC1936 and AD brains

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