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Table 4 Genes implicated in DNA repair that were down regulated in SMAv motor neurons compared to both SMAr and WTv

From: Transcriptional profiling of differentially vulnerable motor neurons at pre-symptomatic stage in the Smn 2b/- mouse model of spinal muscular atrophy

Gene symbol

Log2 fold change

 

SMAv vs. WTv

SMAv vs. SMAr

EYA1

−3.0

−3.1

C230052I12RIK

−2.2

−1.7

SREBF1

−1.8

−1.9

CHD3

−1.5

−1.8

FTSJD2

−1.2

−1.1

CHD8

−1.2

−1.1

KDM1B

−1.2

−1.6

BRE

−1.1

−1.2

HBB-B1

−1.1

−1.7

MLH3

−1.0

−1.3

MLL5

−0.9

−1.1

ARPP21

−0.6

−1.8