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Table 3 Frequency of WHO criteria in the different tumor subtypes

From: Histological criteria for atypical pituitary adenomas – data from the German pituitary adenoma registry suggests modifications

  Subgroups All Patients
TPAs APAs PCAs Total
N= Mean N= Mean N= Mean N= Mean
Mitotic index (in 10 HPF) 200 1 98 7 10 3 308 3
p53 pos. Nuclei (%) 200 1 98 8 10 8 308 3
Ki-67 pos. Nuclei (%) 200 1 98 9 10 7 308 4
Growth pattern Non invasive 77 - 8 - 0 - 85 -
Invasive 68 - 58 - 10 - 136 -
  1. Overview of metric and dichotomous parameters analyzed in the subgroups of pituitary tumors analyzed
  2. N number, HPF High power field, TPA typical pituitary adenomas, APA atypical pituitary adenomas, PCA pituitary carcinomas
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