No neuropathological evidence for a direct topographical relation between microbleeds and cerebral amyloid angiopathy

Table 2 Frequencies of CAA and CMB and mean CAA severities depending on neuropathological diagnosis

Neuropathologial diagnosis	No of cases	Prevalence of CAA (%)	Prevalence of CMB (%)	Mean severity of CAA
AD	14	71	78	1.5
Va	29	55	93	1.2
AD + Va	11	63	91	1.7
C	34	38	91	0.7
Others	25	16	100	0.5

AD Alzheimer’s disease, Va vascular encephalopathy, AD + Va mixed (AD-type and vascular encephalopathy), C no brain lesions, Others = any type of Lewy body pathology as Parkinson’s disease, Lewy body dementia – 8 cases, or multiple system atrophy (1 case), amyotrophic lateral sclerosis (2 cases) or brain metastases (14 cases)

ISSN: 2051-5960