From: Visualization of regional tau deposits using 3H-THK5117 in Alzheimer brain tissue
Demographic data | |||
---|---|---|---|
Demography | AD Case 1 | AD Case 2 | AD Case 3 |
Onset | EOAD | LOAD | LOAD |
Gender (M/F) | F | F | M |
ApoE alleles (E/E) | 4/4 | 4/4 | 4/4 |
MMSE at time of last PET | 12 | 26 | 25 |
Age at death (years) | 60 | 79 | 81 |
Time between last PET and death (years) | 7 | 7 | 5 |
3H-THK5117 specific binding in regions of interest (fmol/mg) | |||
Regions of interest | AD Case 1 | AD Case 2 | AD Case 3 |
Hippocampus | 693 | 171 | 112 |
Entorhinal cortex | 713 | 126 | 53 |
Fusiform gyrus | 585 | 189 | 52 |
Inferior temporal gyrus | 764 | 125 | 59 |
Middle temporal gyrus | 495 | 140 | 48 |
Superior temporal gyrus | 363 | 114 | 53 |
Insular cortex | 423 | 68 | 50 |
Postcentral gyrus | 312 | 77 | 75 |
Precentral gyrus | 310 | 32 | 102 |
Middle frontal gyrus | 276 | 55 | 56 |
Superior frontal gyrus | 344 | 57 | 114 |
Cingulate gyrus | 292 | 120 | 110 |
Putamen | 242 | NA | NA |
Thalamus | 349 | NA | NA |
Amygdala | 507 | NA | NA |