Table 5 TDP-43 distribution in this study
From: Incidence and extent of TDP-43 accumulation in aging human brain
Control elderly | AD | LBD | AGD | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
n = 136 | n = 29 | n = 11 | n = 11 | ||||||||||||||
score | score | score | score | ||||||||||||||
0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | ||
Dentate gyrus | DN | 135 | 0 | 0 | 0 | 20 | 4 | 0 | 1 | 11 | 0 | 0 | 0 | 10 | 0 | 0 | 0 |
GCI | 135 | 0 | 0 | 0 | 20 | 1 | 4 | 0 | 11 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | |
NCI | 135 | 0 | 0 | 0 | 18 | 2 | 2 | 3 | 10 | 1 | 0 | 0 | 10 | 0 | 0 | 0 | |
NII | 135 | 0 | 0 | 0 | 22 | 3 | 0 | 0 | 11 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | |
Uncus (Hippocampus) | DN | 107 | 13 | 12 | 4 | 17 | 4 | 4 | 3 | 6 | 3 | 2 | 0 | 6 | 4 | 1 | 0 |
GCI | 136 | 0 | 0 | 0 | 21 | 0 | 4 | 3 | 10 | 1 | 0 | 0 | 11 | 0 | 0 | 0 | |
NCI | 136 | 0 | 0 | 0 | 17 | 2 | 3 | 6 | 11 | 0 | 0 | 0 | 10 | 0 | 1 | 0 | |
NII | 136 | 0 | 0 | 0 | 27 | 1 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
Pyramidal layer | DN | 136 | 0 | 0 | 0 | 21 | 2 | 3 | 2 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 |
GCI | 136 | 0 | 0 | 0 | 18 | 2 | 5 | 3 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NCI | 135 | 1 | 0 | 0 | 16 | 3 | 6 | 3 | 10 | 1 | 0 | 0 | 11 | 0 | 0 | 0 | |
NII | 136 | 0 | 0 | 0 | 27 | 1 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
Subiculum | DN | 133 | 2 | 1 | 0 | 19 | 5 | 2 | 2 | 9 | 1 | 1 | 0 | 11 | 0 | 0 | 0 |
GCI | 136 | 0 | 0 | 0 | 16 | 4 | 3 | 5 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NCI | 135 | 1 | 0 | 0 | 15 | 3 | 5 | 5 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NII | 136 | 0 | 0 | 0 | 27 | 1 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
Entorhinal cortex | DN | 135 | 0 | 0 | 0 | 17 | 5 | 1 | 5 | 10 | 1 | 0 | 0 | 11 | 0 | 0 | 0 |
GCI | 134 | 1 | 0 | 0 | 17 | 2 | 4 | 5 | 10 | 0 | 1 | 0 | 11 | 0 | 0 | 0 | |
NCI | 135 | 0 | 0 | 0 | 19 | 2 | 3 | 4 | 10 | 0 | 1 | 0 | 11 | 0 | 0 | 0 | |
NII | 135 | 0 | 0 | 0 | 24 | 4 | 0 | 0 | 10 | 1 | 0 | 0 | 11 | 0 | 0 | 0 | |
Amygdala Medial part | DN | 130 | 4 | 0 | 0 | 18 | 4 | 4 | 3 | 10 | 1 | 0 | 0 | 9 | 0 | 1 | 0 |
GCI | 134 | 0 | 0 | 0 | 17 | 3 | 7 | 2 | 10 | 0 | 1 | 0 | 10 | 0 | 0 | 0 | |
NCI | 134 | 0 | 0 | 0 | 18 | 2 | 3 | 6 | 10 | 0 | 1 | 0 | 9 | 1 | 0 | 0 | |
NII | 134 | 0 | 0 | 0 | 28 | 1 | 0 | 0 | 11 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | |
Amygdala Lateral part | DN | 133 | 0 | 0 | 1 | 19 | 7 | 0 | 3 | 10 | 1 | 0 | 0 | 9 | 0 | 1 | 0 |
GCI | 134 | 0 | 0 | 0 | 18 | 4 | 5 | 2 | 10 | 0 | 1 | 0 | 9 | 0 | 1 | 0 | |
NCI | 134 | 0 | 0 | 0 | 18 | 0 | 5 | 6 | 10 | 0 | 1 | 0 | 9 | 0 | 1 | 0 | |
NII | 134 | 0 | 0 | 0 | 28 | 1 | 0 | 0 | 11 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | |
Uncus (Amygdala) | DN | 129 | 3 | 2 | 0 | 15 | 8 | 3 | 3 | 8 | 3 | 0 | 0 | 7 | 2 | 1 | 0 |
GCI | 134 | 0 | 0 | 0 | 16 | 6 | 7 | 0 | 9 | 2 | 0 | 0 | 10 | 0 | 0 | 0 | |
NCI | 134 | 0 | 0 | 0 | 16 | 6 | 3 | 4 | 10 | 1 | 0 | 0 | 9 | 1 | 0 | 0 | |
NII | 134 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | |
Dorsal motor nucleus of the vagus | DN | 136 | 0 | 0 | 0 | 27 | 2 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 |
GCI | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NCI | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NII | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
Nucleus of hypoglossal nerve | DN | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 |
GCI | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NCI | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NII | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
Inferior olivary complex | DN | 122 | 11 | 3 | 0 | 25 | 2 | 2 | 0 | 7 | 4 | 0 | 0 | 9 | 2 | 0 | 0 |
GCI | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NCI | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NII | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
Reticular formation | DN | 132 | 2 | 2 | 0 | 28 | 1 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 |
GCI | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NCI | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NII | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
Pyramids | DN | 135 | 1 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 |
GCI | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NCI | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NII | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
Anterior horn | DN | 129 | 7 | 0 | 0 | 28 | 1 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 |
GCI | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NCI | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NII | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
Posterior horn | DN | 134 | 2 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 |
GCI | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NCI | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NII | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
White matter | DN | 125 | 11 | 0 | 0 | 27 | 2 | 0 | 0 | 11 | 0 | 0 | 0 | 10 | 1 | 0 | 0 |
Central gray matter | DN | 133 | 3 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 |
GC | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NC | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |
NN | 136 | 0 | 0 | 0 | 29 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | |