Table 4 Presence of TDP-43 pathology
From: Incidence and extent of TDP-43 accumulation in aging human brain
Control elderly | AD | LBD | AGD | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
positive | negative | p value | positive | negative | p value | positive | negative | p value | positive | negative | p value | |
Cases (%) | 55 (40 %) | 81 (60 %) | 21 (72.4 %) | 8 (27.6 %) | 8 (72.7 %) | 3 (27.3 %) | 6 (54.5 %) | 5 (45.5 %) | ||||
Male, Female | 41, 14 | 54, 27 | N.S. | 9, 12 | 3, 5 | N.S. | 6, 2 | 3, 0 | N.S. | 2, 4 | 2, 3 | N.S. |
Mean age at death | 80.6 ± 9.3 | 77.1 ± 9.7 | 0.038 | 86.2 ± 6.8 | 85.5 ± 4.5 | N.S. | 85.1 ± 4.6 | 81.0 ± 6.7 | N.S. | 90.3 ± 4.8 | 82.2 ± 4.7 | 0.028 |
(years, mean ± SD) | ||||||||||||
Mean brain weight | 1254 ± 115 | 1259 ± 37 | N.S. | 1168 ± 208 | 1169 ± 103 | N.S. | 1217 ± 57.2 | 1184 ± 111 | N.S. | 1149 ± 105 | 1171 ± 153 | N.S. |
(grams, mean ± SD) | ||||||||||||