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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Distinct pathological phenotypes of Creutzfeldt-Jakob disease in recipients of prion-contaminated growth hormone

Fig. 3

Histopathology and immunohistochemistry of GH-CJDMM1 (cases 2 and 3), dCJDMM1 (case 4) and sCJDMM1. Histopathology (rows i-ii) and PrP immunohistochemistry (row iii). i: No spongiform degeneration (SD) (case 2) and fine SD (cases 3, 4 and sCJDMM1). ii: Focal SD (cases 2, 4 and sCJDMM1) and ubiquitous SD (case 3). Insets contain magnified regions delimited by rectangles in the main figure. iii: “Brush stroke-like” PrP immunostaining pattern (cases 2, 3, 4 and sCJDMM1). Scale bar of insets in ii: 100 μm; mol. L.: molecular layer; grl. L.: granular layer; antibody in iii: 3F4

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Acta Neuropathologica Communications

ISSN: 2051-5960

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