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Table 2 Distribution and frequency of Schwann cell cytoplasmic inclusions (SCCIs) in patients with multiple system atrophy

From: Filamentous aggregations of phosphorylated α-synuclein in Schwann cells (Schwann cell cytoplasmic inclusions) in multiple system atrophy

Case No. Cranial nerves Spinal nerves DRG SG Visceral organs
C T L S    
  III V IX/X XII A P A P A P A P   
1 NE + + NE NE + + ++ ++ + NE NE + (stomach)
2
3 NE + + + + + +
4 + NE NE NE + + + NE NE
5 + NE + + + +
6 NE NE + + + +
7 NE NE + + +
8 ++ NE + NE + +
9 NE + NE + + + + + NE NE
10 NE NE + + + +
11 NE + + +
12 NE NE + (adrenal, urinary bladder)
13 NE NE + + +
14 NE NE NE NE NE NE
Percent positive for inclusions 28.6 0 46.2 9.1 41.7 0 42.9 14.3 28.6 7.1 69.2 30.8 66.7 33.3 14.3
  1. DRG, dorsal root ganglia; SG, sympathetic ganglia; C, cervical; T, thoracic; L, lumbar; S, sacral; A, anterior; P, posterior. Semiquantitive assessment:−, none; +, 1 to 5 SCCIs per area; ++, more than 5 SCCIs per area; NE, not examined