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Figure 1 | Acta Neuropathologica Communications

Figure 1

From: Degeneration of spinal motor neurons by chronic AMPA-induced excitotoxicity in vivo and protection by energy substrates

Figure 1

Progressive alterations of the rear limbs induced by AMPA and protection by energy substrates. Representative posterior views of the rear limbs (C, contralateral; I, ipsilateral) and hind paw footprints (red, ipsilateral; black, contralateral) at the initial (day 1), the middle (day 4) and last day (day 7) of treatment. The AMPA-induced progressive alterations were prevented by pyruvate and βHB but not by ascorbate and GEE alone (not shown) or in combination (antioxidant mixture).

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Acta Neuropathologica Communications

ISSN: 2051-5960

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