Figure 7From: PGC-1α activity in nigral dopamine neurons determines vulnerability to α-synuclein Co-injection of AAV-aSyn and AAV-PGC-1α vectors induces expression of PGC-1α and aSyn in nigral neurons. Immunostaining shows the co-expression of PGC-1α and aSyn in TH-positive neurons in the SNpc of PGC1α-KO mice, at 6 months post-AAV injection. Scale bar: 20 μm.Back to article page