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Figure 1 | Acta Neuropathologica Communications

Figure 1

From: PGC-1α activity in nigral dopamine neurons determines vulnerability to α-synuclein

Figure 1

Expression of PGC-1α and PGC-1β in PGC1α-KO mice. (a) Level of PGC-1α mRNA in the SN of WT mice, PGC-1α KO mice (PGC1α-KO) and from PGC1α-KO mice injected with a vector encoding PGC-1α (PGC1α Inj) at 1 month post-injection. Values are expressed in arbitrary units (AU). WT n = 2; PGC1α-KO n = 5; PGC1α Inj n = 3. (b) Level of PGC-1β mRNA in the SN. Values are expressed in arbitrary units (AU). WT n = 3; PGC1α-KO n = 3; PGC1α Inj n = 3. Statistical analysis: one-way ANOVA with Newman-Keuls post-hoc test; *p < 0.05.

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