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Figure 3 | Acta Neuropathologica Communications

Figure 3

From: Loss of angiotensin II receptor expression in dopamine neurons in Parkinson’s disease correlates with pathological progression and is accompanied by increases in Nox4- and 8-OH guanosine-related nucleic acid oxidation and caspase-3 activation

Figure 3

The number of TH-positive neurons counted in matrix and nigrosome 1 areas of SN in neurologically intact individuals (AMC) and in prePD and in PD patients. TH+ neurons were examined in two 9.0 mm2 areas of the SN, viz., in the matrix region, which is calbindin-rich, and nigrosome 1, a calbindin-poor region. Data are expressed as mean ± SEM; * denotes significant differences (p < 0.05) between nigrosome 1 in prePD and in PD as compared to AMC. The number of TH+ neurons in the matrix was not significantly altered with clinical diagnosis.

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Acta Neuropathologica Communications

ISSN: 2051-5960

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