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Figure 1 | Acta Neuropathologica Communications

Figure 1

From: Loss of angiotensin II receptor expression in dopamine neurons in Parkinson’s disease correlates with pathological progression and is accompanied by increases in Nox4- and 8-OH guanosine-related nucleic acid oxidation and caspase-3 activation

Figure 1

Nigrosomes at specific rostrocaudal levels of the adult human SN. Nigrosomes were identified in all 15 patients examined by Calbindin D28k immunohistochemistry in the intermediate (A, C, and E) and caudal (B, D, and F) SN. In these negative images, nigrosomes are depicted as dark areas (i.e., calbindin-poor) and numbered 1–4. Matrix is calbindin-rich and appears white. We have examined one AOI for nigrosome 1 and another AOI for matrix for each case studied. Substantia nigra (SN); Red nucleus (RN). Scale bar is 1000 μm.

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Acta Neuropathologica Communications

ISSN: 2051-5960

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