Figure 7
Decreased AChE levels in prion-infected MovS6 cells. a Western blot analysis of AChE levels in infected cells harboring PK-resistant PrPS. PrPSc accumulation was determined with the anti-PrP antibody Sha31b; the anti-β-actin antibody was used to control protein loading. Ctr, mock-infected cells. Molecular weights (in kilodaltons) are indicated on the left of the blots. b Quantification of AChE protein (orange bars) and enzymatic activity (green bars) in mock-infected (Ctr) and prion-infected MovS6 cells. Values are presented as fold change relative to control cells. Data are the mean ± SEM of four independent experiments for each condition. *P < 0.05 one-way ANOVA.