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Table 3 Distribution of analyzed protein targets from autism subjects relative to controls

From: Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid

  Autism patients with no seizure disorder Autism patients with seizure disorder
  AN01093 (A1) AN00764 (A3) AN00493 (A6) UMB1182 (A9) AN06420 (A5) UMB797 (A8) AN08873 (A7) UMB1174 (A2) AN08792 (A4) AN16641 (A10) AN16615 (A11)
TrkB-FL −2.0 SD −1.5 SD −2.0 SD −1.5 SD 0.5 SD −0.5 SD 0.5 SD −2.0 SD −2.0 SD −1.5 SD −1.5 SD
PI3K p85 −2.0 SD −1.5 SD −2.0 SD −2.0 SD 0.5 SD −0.5 SD 0.5 SD −2.0 SD −2.0 SD 1.5 SD −1.5 SD
Akt −2.0 SD −0.5 SD −1.5 SD −2.0 SD 1.5 SD −0.5 SD 0.5 SD −1.5 SD −1.5 SD −0.5 SD −1.5 SD
mTOR −2.0 SD −2.0 SD −2.0 SD −2.0 SD 1.5 SD −0.5 SD 0.5 SD −2.0 SD −2.0 SD −1.5 SD −2.0 SD
Phospho-mTOR −1.5 SD −2.0 SD −2.0 SD −2.0 SD 0.5 SD −0.5 SD −0.5 SD −2.0 SD −2.0 SD −2.0 SD −2.0 SD
p70 S6
Kinase
−2.0 SD −1.5 SD −1.5 SD −2.0 SD 0.5 SD −0.5 SD −0.5 SD −1.5 SD −2.0 SD −1.5 SD −1.5 SD
eIF4B −2.0 SD −2.0 SD −2.0 SD −1.5 SD 1.5 SD 2.0 SD −0.5 SD −1.5 SD −2.0 SD −2.0 SD −2.0 SD
PSD-95 −1.5 SD −1.5 SD −1.5 SD −1.5 SD 0.5 SD 0.5 SD 0.5 SD −1.5 SD −1.5 SD −1.5 SD −1.5 SD
  1. SD = Standard deviation. The mean of each target for the control group was used as a reference to calculate the corresponding standard deviation values for each target. Bold-Italics = 0.5-2.0 standard deviations less than the mean of controls. Not Bold = 0.5-2.0 standard deviations greater than the mean of controls.