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Table 2 The difference between the mean volume of neuronal cytoplasm in autistic and control cohorts

From: Neuronal nucleus and cytoplasm volume deficit in children with autism and volume increase in adolescents and adults

Brain structure 4- to 8-year-old subjects 11- to 23-year-old subjects 29- to 64-year-old subjects
Control Autism Control Autism Control Autism
Mean ± SD (100%) Mean ± SD (%) Mean ± SD (100%) Mean ± SD (%) Mean (SD) (100%) Mean ± SD (%)
Nucleus accumbens 900 ± 108 615 ± 122 -32% 864 ± 113 808 ± 46 -6% 758 ± 113 849 ± 242 + 12%
Purkinje cells 11,060 ± 466 7,653 ± 2,176 -31% 10,899 ± 1,261 9,222 ± 358 -15% 10,275 ± 1,434 7,735 ± 860 -25%
Claustrum 1,599 ± 167 1,173 ± 230 -27% 1,589 ± 75 1,358 ± 129 -15% 1,518 ± 180 1,415 ± 124 -7%
Thalamus 3,057 ± 220 2,311 ± 225 -24% 2,696 ± 255 2,617 ± 283 -3% 2,768 ± 214 2,954 ± 218 + 7%
Globus pallidus 5,011 ± 190 3,999 ± 336 -20% 4,061 ± 864 3,875 ± 660 -5% 4,523 ± 935 4,441 ± 1,008 -2%
Dentate nucleus 7,734 ± 974 5,913 ± 1,168 -23% 7,883 ± 751 6,617 ± 951 -16% 7,335 ± 516 6,505 ± 2,047 -11%
Entorhinal cortex 1,862 ± 167 1,434 ± 178 -23% 1,948 ± 135 1,597 ± 186 -18% 1,969 ± 102 1,980 ± 432 + 1%
Amygdala 2,427 ± 125 1,878 ± 287 -23% 2,386 ± 56 2,153 ± 282 -10% 2,398 ± 256 2,054 ± 413 -14%
Magnocellular basal complex 7,728 + 475 6,076 ± 302 -21% 7,639 ± 750 7,489 ± 556 -2% 7,867 ± 1,087 7,563 ± 1,028 -4%
Putamen 1,071 ± 105 914 ± 92 -15% 820 ± 163 758 ± 125 -8% 679 ± 98 770 ± 165 + 13%
Caudate nucleus 943 ± 106 754 ± 93 -20% 988 ± 148 958 ± 103 -3% 874 ± 160 983 ± 165 + 12%
Inferior olive 3,852 ± 1,428 3,325 ± 352 -14% 3,136 ± 677 3,619 ± 575 + 15% 3,409 ± 616 3,668 ± 72 + 8%
Magnocellular LGN 4,786 ± 266 4,261 ± 665 -11% 5,010 ± 87 4,855 ± 695 -3% 5,119 ± 655 5,230 ± 473 + 2%
Parvocellular LGN 2,337 ± 280 2,249 ± 316 -4% 2,563 ± 156 2,260 ± 378 -12% 2,547 ± 356 2,614 ± 445 + 3%
Substantia nigra 8,193 ± 1,344 7,847 ± 615 -4% 8,147 ± 487 8,271 ± 730 + 1% 8,679 ± 2,270 10,416 ± 1,146 + 20%
Ammon’s horn 2,712 ± 152 2,444 + 494 -10% 2,972 ± 221 2,515 ± 297 -3% 2,892 ± 452 2,752 ± 718 -5%
  1. Mean cytoplasm volume ± SD; LGN, lateral geniculate nucleus.