Figure 8From: LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease α-synuclein is not accumulated in the absence of LAMP-2 expression. (a/b) Immunoblots and respective densitometric quantification of soluble and insoluble fractions from cortices (a) and hippocampi (b) of LAMP-2-deficient (LAMP-2-/y) mice and their wild-type (WT) littermates. The asterisk highlights a non-specific band recognized by the α-syn antibody (C-20, Santa Cruz; NSE or actin were used as loading controls).Back to article page