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Figure 6 | Acta Neuropathologica Communications

Figure 6

From: Glial cells in familial amyloidotic polyneuropathy

Figure 6

TTR is expressed by colon of the Hsf/V30M FAP mouse model. A) Photomicrographs illustrating TTR staining in liver of Hsf/V30M mice, treated with TTR siRNA or vehicle; scale bar 50 μm. B) Histogram represents TTR mRNA levels in liver of Hsf/V30M mice treated with TTR siRNA as compared with control animals receiving only vehicle. Data was normalized using 18S as the housekeeping gene (p*** < 0.001). C) Histological images of colonic myenteric plexus from Hsf/V30M mice treated with TTR siRNA as compared with vehicle treated animals. Scale bar 20 μm. D) Histogram denoting TTR mRNA expression in colon from Hsf/V30M mice treated with vehicle or siRNA and Ttr mRNA from WT animals. Data was normalized using 18S as the housekeeping gene (p** < 0.01).

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