Glial cells from DRG internalize TTR, in a mouse model of FAP. A) Double immunofluorescence of TTR (green) and S100 (red), a marker for glial cells, in DRG of Hsf/V30M mice, showing TTR localized inside satellite cells. Scale bar 20 μm; higher magnification 5 μm. B) TTR colocalizing with EEA1 in satellite cells from DRG of Hsf/V30M animals. Scale bar 20 μm; higher magnification 5 μm. C) Representative confocal image demonstrating colocalization between TTR (green) and lysosomes (Lamp1; red) in satellite cells from DRG (arrows). Scale bar 8 μm.