Figure 3From: Sporadic hemangioblastomas are characterized by cryptic VHL inactivation Whole exome sequencing of sporadic cerebellar and spinal cord hemangioblastomas reveals recurrent VHL inactivation. The VHL locus was noted to have non-synonymous mutations (green), copy neutral LOH (empty blue box), or hemizygous deletion (filled blue box) in 8/10 samples in the discovery cohort.Back to article page