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Table 1 Demographic features of cases with AD, normal aging, and CBD

From: Ultrastructural differences in pretangles between Alzheimer disease and corticobasal degeneration revealed by comparative light and electron microscopy

  Pathological diagnosis Age of death (y)/sex Brain weight (g) Duration (y) Braak NFT stage Clinical symptoms Type of tau-positive inclusions investigated
Case 1 Normal aging 73/F 1,260 na I No history of dementia or motor symptoms Pretangles, NFTs
Case 2 AD 58/F 850 14 VI Severe dementia, disorientation Pretangles, NFTs
Case 3 CBD 60/M 1,145 7 I Supranuclear gaze palsy, frequent fall, parkinsonism, frontal signs Pretangles, Pick-like inclusions*
Case 4 CBD 70/F 770 11 III Frontotemporal dementia, parkinsonism Pretangles, Pick-like inclusions, ballooned neurons
  1. *Pick-like inclusions denoting densely packed round inclusions usually observed in the small-sized cortical neurons in corticobasal degeneration; AD, Alzheimer disease; CBD, corticobasal degeneration; NFT, neurofibrillary tangle.