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Table 1 List of patient tumor-derived orthotopic xenograft mouse models

From: Silencing BMI1 eliminates tumor formation of pediatric glioma CD133+ cells not by affecting known targets but by down-regulating a novel set of core genes

Model ID

Age

Gender

Diagnosis

BMI1

Ref

IC-3704GBM

12 y

M

GBM (small cell variant)

+

[50]

IC-3752GBM

5 y

F

GBM

+

[50]

IC-1621GBM

6 y

M

GBM

+

[50]

IC-1502GBM

4 y 8 mo

F

GBM (giant cell )

+

[50]

IC-1406GBM

5 y

F

GBM

++

[50]

IC-2305GBM

9 y

M

GBM (small cell variant)

+++

[50]

IC-1128GBM

8 y 7 mo

M

GBM

++

[45]

ICb-1227AA

16 y 11 mo

F

Anaplastic Astrocytoma-(radiation induced)

++

[45]

  1. Note: IC: intracerebral; ICb: intracerebellar.