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Table 1 Clinical and pathological features of ET cases and control

From: Decreased EAAT2 protein expression in the essential tremor cerebellar cortex

  Western blot analysis Immunohistochemistry
  ET Controls ET Controls
n 16 13 10 12
Age at death (years) 83.6 ± 5.5 79.7 ± 7.1 85.7 ± 5.9 81.5 ± 6.4
Female gender 11 (68.8%) 8 (61.5%) 8 (80.0%) 10 (83.3%)
Age of tremor onset 30.9 ± 21.4 NA 42.0 ± 30.5 NA
Disease duration 53.4 ± 26.0 NA 44.3 ± 31.8 NA
Total tremor scores 23.8 ± 10.5 NA 24.8 ± 12.9 NA
Presence of head tremor 9 (56.3%) NA 8 (80.0%) NA
Presence of voice tremor 4 (25.0%) NA 4 (40.0%) NA
Family history of tremor 8 (50.0%) NA 8 (80.0%) NA
Brain weight (grams) 1170 ± 155 1181 ± 173 1138 ± 192 1174 ± 140
Postmortem interval (hours) 3.2 ± 4.7 5.9 ± 2.7 3.5 ± 5.8 9.7 ± 10.6
Axonal torpedoes 22.1 ± 20.7** 4.6 ± 7.7 12.7 ± 9.8** 6.8 ± 4.3
Purkinje Cell Count 6.5 ± 1.6** 10.2 ± 2.3 7.1 ± 1.6* 9.4 ± 2.2
  1. *p < 0.05.
  2. **p < 0.01.