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Table 1 Clinical and pathological features of ET cases and control

From: Decreased EAAT2 protein expression in the essential tremor cerebellar cortex

 

Western blot analysis

Immunohistochemistry

 

ET

Controls

ET

Controls

n

16

13

10

12

Age at death (years)

83.6 ± 5.5

79.7 ± 7.1

85.7 ± 5.9

81.5 ± 6.4

Female gender

11 (68.8%)

8 (61.5%)

8 (80.0%)

10 (83.3%)

Age of tremor onset

30.9 ± 21.4

NA

42.0 ± 30.5

NA

Disease duration

53.4 ± 26.0

NA

44.3 ± 31.8

NA

Total tremor scores

23.8 ± 10.5

NA

24.8 ± 12.9

NA

Presence of head tremor

9 (56.3%)

NA

8 (80.0%)

NA

Presence of voice tremor

4 (25.0%)

NA

4 (40.0%)

NA

Family history of tremor

8 (50.0%)

NA

8 (80.0%)

NA

Brain weight (grams)

1170 ± 155

1181 ± 173

1138 ± 192

1174 ± 140

Postmortem interval (hours)

3.2 ± 4.7

5.9 ± 2.7

3.5 ± 5.8

9.7 ± 10.6

Axonal torpedoes

22.1 ± 20.7**

4.6 ± 7.7

12.7 ± 9.8**

6.8 ± 4.3

Purkinje Cell Count

6.5 ± 1.6**

10.2 ± 2.3

7.1 ± 1.6*

9.4 ± 2.2

  1. *p < 0.05.
  2. **p < 0.01.