In MS white matter, kif21b is approximately ten-fold increased compared with NDC white matter. Kif21b expression in the white matter of 16 MS and 11 NDC was determined. MS patients had approximately ten-fold increased kif21b expression compared with NDC (white bars). As a reference, the kif21b cortical expression levels are shown (grey bars). In MS patients, kif21b white matter expression equalled kif21b grey matter expression, whereas in NDC kif21b expression in the white matter compared with the grey matter was significantly lower.