Figure 3
From: Axial mitochondrial myopathy in a patient with rapidly progressive adult-onset scoliosis
Mitochondrial respiratory chain immunofluorescence. Immunofluorescence staining (green) for Complex I (30 kD NDUFS3) [(a) and (g)], Complex II (30 kD FeS protein) (b), Complex III (core 2) (c), Complex IV-I (IV subunit I) (d), Complex IV-IV (IV subunit IV) [(e) and (h)], and Complex V (OSCP) (f); immunofluorescence staining for porin (red) is a reference control for mitochondrial density and distribution. Arrows, examples of partially deficient fibers; arrowheads, examples of totally deficient fibers; asterisk, an example of the area with fibers showing mitochondrial hypodensity. Original magnification: a-f, 100x; g-h, 400x.