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Table 1 8 Genes associated with brainstem gliomagenesis but not cerebral cortex gliomagenesis and differentially expressed between Brainstem Glioma (BSG) and Cerebral Cortex Glioma (CG) in the mouse

From: Pax3 expression enhances PDGF-B-induced brainstem gliomagenesis and characterizes a subset of brainstem glioma

Gene symbol

Gene title

Fold-change BSG vs NBS

p-value

Fold-change BSG vs CG

p-value

Pax3

paired box gene 3

4.96

1.04E-05

8.44

1.20E-06

Pax3

paired box gene 3

3.87

2.19E-04

6.32

2.45E-05

Irx5

Iroquois related homeobox 5 (Drosophila)

3.35

2.67E-03

19.01

6.15E-06

Pax3

paired box gene 3

2.61

2.86E-04

3.70

3.24E-05

Pcyt1b

phosphate cytidylyltransferase 1, choline, beta isoform

2.49

1.11E-05

2.46

1.24E-05

4933436C20Rik

RIKEN cDNA 4933436C20 gene

2.47

4.35E-05

2.99

1.08E-05

Myo5b

myosin VB

−2.41

5.53E-03

−7.59

2.41E-05

Bmp4

bone morphogenetic protein 4

−2.57

3.47E-07

−2.77

1.94E-07

Chl1

cell adhesion molecule with homology to L1CAM

−7.21

2.66E-06

−12.91

3.66E-07

Al314604

expressed sequence Al314604

−45.25

8.64E-11

−8.89

7.21E-09

  1. Genes in bold are also differentially expressed between Olig2-eGFP-L10a BSG and CG (See Additional file 5: Table S4). NBS = Normal brainstem.