Figure 9

Histological evaluation of total tau. Representative images of HT7 immunostained cortical and hippocampal brain sections from control and treated mice ( A - H ), and subsequent semiquantitative analysis ( I - L ) did not reveal any significant differences in total tau levels between CpG ODN-treated and vehicle-treated Tg animals in both study groups. Scale bars (100 µm) in B and F correspond to cortical images A, B, E, F. Scale bars in D and H correspond to hippocampal images C, D, G, H.