Figure 8

Conserved elements of neurodegeneration. (A) Schematic diagram of conserved elements of neurodegeneration. Select CNM genes of interest are shown in black text. Predicted hub genes and upstream transcription factors shown in green text. (B) Forest plots for highlighted candidate novel genes of interest. Forest plot x-axes show standardized mean difference (Hedges’ g in log2 scale) for genes in multiple data sets. Blue box sizes are inversely proportional to the SEM difference of the gene in each data set. Whiskers denote 95% confidence interval. Yellow diamonds represent combined mean difference for each gene. Yellow diamond width denotes 95% confidence interval.