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Table 1 Clinical and neuropathological information of all included subjects

From: Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson’s disease patients

     Braak staging    
C# Sex Age PMD (hrs) AD (NFT / Aβ) PD (α-syn) D Region Cause of death
1 F 92 7:00 1A 0 NDC HC + SN Acute death, pulmonary emboly
2 M 88 4:23 2A 0 NDC HC + SN Gastro-intestinal bleeding
3 F 84 6:55 1O 0 NDC HC + SN Myelodysplasia
4 M 82 5:10 1O 0 NDC HC + SN Unknown
5 M 62 7:20 1O 0 NDC HC + SN Unknown
6 F 77 2:55 1B 0 NDC SN Pulmonary metastasis
7 M 84 5:35 1A 0 NDC SN Heart failure
8 M 75 4:15 1B 0 NDC SN Respiratory insufficiency
9 M 71 6:00 2(−) 0 NDC SN Respiratory insufficiency
10 M 81 7:55 2O 0 NDC SN Renal insufficiency
11 F 78 7:30 2(−) 0 NDC SN Heart failure
12 M 79 6:00 1B 0 NDC SN Metastates prostate and lung cancer
13 F 83 8:00 1O 0 NDC SN Respitatory insuffisiency
14 F 83 3:20 1B 0 NDC HC Legal Euthanasia
15 F 84 4:45 1O 0 NDC HC Heart failure
16 F 85 5:19 2B 0 NDC HC Natural death, pulmonary disease
17 M 78 <17:00 1O 0 NDC HC Natural cause,
18 F 82 5:10 2O 2 iLBD HC + SN Heartfailure
19 M 86 4:00 2B 1 iLBD HC + SN Respiratory insufficiency
20 M 56 5:00 0(−) 2 iLBD HC + SN Pneunomia
21 F 91 4:50 (−) 1 iLBD HC + SN Exhaustion, colon carcinoma
22 M 84 7:20 1B 3 iLBD HC + SN Prostate cancer
23 F 82 7:00 1O 3 iLBD SN Pneunomia
24 F 85 4:40 2A 1 iLBD SN Dehydration
25 F 93 <10:00 0(−) 1 iLBD SN Unknown
26 F 78 <10:00 0(−) 1 iLBD SN Unknown
27 M 87 10:20 1A 1 iLBD HC Pneunomia, heart failure
28 M 83 4:50 1A 4 PDD HC + SN Heartfailure
29 F 59 9:35 1A 4 PD HC + SN Shock due to blood loss in digestive tract
30 F 90 4:50 1B 4 PDD HC + SN Unknown
31 M 84 9:00 1A 5 PDD HC + SN Pneunomia and dehydration
32 F 70 7:05 2B 6 PDD HC + SN Haematemesis by oesophagitis
33 F 87 5:25 2B 6 PDD HC + SN Pneunomia
34 M 73 5:35 1A 5 PDD HC + SN Direct cause unknown (morphine)
35 M 83 5:15 1B 6 PDD HC + SN Pneunomia
36 F 84 7:25 2B 5 PD HC + SN Old age, shortness of breath
37 F 96 7:10 1B 5 PD HC + SN Old age
38 M 86 5:10 2B 5 PD HC + SN Heartfailure
39 M 71 5:50 1A 6 PD HC + SN Respiratory failure
40 M 86 5:35 1O 4 PD SN Aspiration pneumonia
41 M 80 7:05 1B 6 PDD SN Unknown, possibly urine tract infection
42 F 83 6:05 1O 4 PDD HC Cachexia by dementia, infarction
43 M 83 6:35 1B 6 PDD HC Pneunomia
  1. D, clinical diagnosis; PMD, post mortem delay; NFT, neurofibrillary tangles; Aβ amyloid beta; α-syn, alpha synucleine; NDC, non-demented control subject; iLBD, incidental Lewy Body Disease cases; PD, Parkinson’s disease; PDD, Parkinson’s disease with dementia; HC, hippocampus, SN, substantia nigra.