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Table 2 Correlations between white matter Aβ 40/42 levels (Anterior and posterior) and plaque severity rating, assayed by CERAD criteria, in several CNS regions

From: Soluble amyloid beta levels are elevated in the white matter of Alzheimer’s patients, independent of cortical plaque severity

 

Ant. Aβ-40

Post. Aβ-40

Ant. Aβ-42

Post. Aβ-42

r

p

r

p

r

p

r

p

Mid-frontal

0.294

0.196

0.204

0.403

0.697

<0.001

0.630

0.004

Superior temporal

-0.263

0.529

0.194

0.617

0.607

0.111

0.706

0.034

Pre-central

0.042

0.862

0.244

0.329

0.497

0.026

0.413

0.087

Inferior Parietal

0.351

0.118

0.228

0.347

0.744

<0.001

0.633

0.004

Hipp-CA1

0.019

0.937

0.082

0.746

0.618

0.004

0.596

0.009

Subiculum

0.282

0.228

0.347

0.159

0.457

0.043

0.448

0.062

Entorhinal

0.227

0.336

0.348

0.158

0.478

0.033

0.498

0.035

Transentorhinal

0.220

0.352

0.349

0.155

0.565

0.009

0.584

0.011

Inferior Temporal

0.270

0.250

0.298

0.230

0.653

0.002

0.655

0.003

Amygdala

0.365

0.103

0.132

0.591

0.618

0.003

0.482

0.037

Basal forebrain

0.360

0.109

-.024

0.922

0.442

0.045

0.169

0.488

  1. Note: Significant correlations are indicated by bolded text.