Table 4 Ratios of p75 ^NTR /Trks in hippocampal subfields of MTLE groups and normal controls

TrkA

Granular layer

2.4 ± 1.1

1.4 ± 0.4

2.1 ± 1.4

1.0 ± 0.5

0.04 (MTLE × CTRL)

Hilus

2.3 ± 2.0

1.4 ± 0.5

1.5 ± 0.5

0.8 ± 0.4

0.04 (MTLE × CTRL)

CA4

1.9 ± 0.8

1.4 ± 0.4

1.9 ± 0.6

0.9 ± 0.3

0.04 (MTLE and MTLE + P × CTRL)

CA3

1.9 ± 1.0

2.3 ± 0.9

2.6 ± 1.0

1.1 ± 0.6

n.s.

CA2

2.6 ± 1.2

1.7 ± 0.5

2.1 ± 0.6

1.1 ± 0.6

0.04 (MTLE x CTRL)

CA1

2.6 ± 1.4

2.6 ± 0.9

2.3 ± 1.1

0.9 ± 0.5

0.04 (MTLE and MTLE + D × CTRL)

Prosubiculum

2.1 ± 1.2

2.1 ± 1.0

1.9 ± 0.3

1.0 ± 0.4

n.s.

Subiculum

2.3 ± 1.0

1.5 ± 0.5

1.8 ± 0.6

0.9 ± 0.5

0.005 (MTLE x CTRL)

Parasubiculum

2.2 ± 0.6

2.3 ± 0.6

1.8 ± 0.4

1.1 ± 0.5

0.004 (MTLE and MTLE + D × CTRL)

Entorhinal cortex

2.3 ± 0.8

3.5 ± 2.1

2.4 ± 1.0

0.9 ± 0.4

0.02 (MTLE + D × CTRL)

TrkB

Granular layer

2.2 ± 0.9

0.9 ± 0.5

0.8 ± 0.5

0.6 ± 0.2

<0.0001 (MTLE × all groups)

Hilus

1.6 ± 1.1

0.9 ± 0.4

0.7 ± 0.2

0.6 ± 0.1

0.01 (MTLE × MTLE + P); 0.02 (MTLE × CTRL)

CA4

2.1 ± 1.0

0.9 ± 0.4

0.8 ± 0.2

0.5 ± 0.1

<0.003 (MTLE × all groups)

CA3

1.7 ± 0.9

2.0 ± 1.0

1.0 ± 0.4

0.6 ± 0.2

0.04 (MTLE and MTLE + D × CTRL)

CA2

2.1 ± 1.3

1.3 ± 0.4

1.1 ± 0.2

0.6 ± 0.1

0.01 (MTLE × CTRL)

CA1

2.1 ± 0.8

1.5 ± 0.4

1.5 ± 0.5

0.6 ± 0.2

<0.0001 (MTLE × CTRL)

Prosubiculum

2.1 ± 0.5

1.4 ± 0.4

1.2 ± 0.3

0.7 ± 0.1

<0.01 (MTLE × all groups); 0.03 (MTLE + D × CTRL)

Subiculum

2.1 ± 0.8

1.0 ± 0.4

0.9 ± 0.3

0.6 ± 0.3

<0.0001 (MTLE × all groups)

Parasubiculum

2.3 ± 0.7

1.2 ± 0.4

1.0 ± 0.2

0.6 ± 0.2

<0.0001 (MTLE × all groups)

Entorhinal cortex

1.9 ± 0.4

1.1 ± 0.4

1.3 ± 0.4

0.5 ± 0.1

0.01 (MTLE × MTLE + D); <0.01 (MTLE groups × CTRL)

TrkC

Granular layer

3.4 ± 1.7

3.0 ± 1.1

2.9 ± 1.2

1.6 ± 0.7

<0.01 (MTLE groups × CTRL)

Hilus

2.0 ± 1.0

1.5 ± 0.5

1.6 ± 0.3

0.8 ± 0.2

0.009 (MTLE × CTRL)

CA4

2.3 ± 1.2

1.6 ± 0.6

1.7 ± 0.6

1.0 ± 0.4

n.s.

CA3

2.0 ± 0.7

2.4 ± 0.4

1.7 ± 0.4

1.1 ± 0.5

<0.01 (MTLE and MTLE + D × CTRL)

CA2

2.2 ± 0.8

2.4 ± 0.4

1.7 ± 0.4

1.1 ± 0.5

0.02 (MTLE and MTLE + D × CTRL)

CA1

2.9 ± 1.3

2.7 ± 1.8

2.4 ± 0.7

1.3 ± 0.7

n.s.

Prosubiculum

2.2 ± 1.1

1.7 ± 0.4

2.2 ± 1.0

1.7 ± 1.2

n.s.

Subiculum

2.7 ± 1.1

2.1 ± 0.5

2.2 ± 1.3

1.1 ± 0.3

n.s.

Parasubiculum

2.7 ± 0.5

2.7 ± 0.5

2.4 ± 0.8

1.3 ± 0.5

<0.01 (MTLE groups × CTRL)

Entorhinal cortex

2.2 ± 0.5

2.4 ± 0.9

2.9 ± 1.0

1.1 ± 0.5

0.03 (MTLE + P × CTRL)