Table 2 Summary of neuropathological data

Neuronal density (#/mm ³ × 10 ³ )

Granular layer

87.1 ± 30.5

87.7 ± 36.6

89.9 ± 34.0

171.5 ± 39.5

Hilus

4.8 ± 3.4

5.1 ± 4.3

5.6 ± 3.9

13.9 ± 5.9

CA4

10.6 ± 7.9

8.8 ± 7.5

7.9 ± 4.1

23.6 ± 8.2

CA3

15.1 ± 10.5

11.7 ± 9.4

14.8 ± 8.9

22.9 ± 6.4

CA2

17.7 ± 10.3

15.9 ± 5.4

11.9 ± 5.8

22.8 ± 8.2

CA1

7.9 ± 5.4

3.7 ± 2.5

2.9 ± 2.4

18.3 ± 8.1

Prosubiculum

11.4 ± 6.1

7.8 ± 4.2

6.2 ± 4.0

23.7 ± 6.2

Subiculum

21.5 ± 9.7

20.0 ± 12.6

16.0 ± 10.6

17.6 ± 7.4

Parasubiculum

17.3 ± 8.1

14.9 ± 8.3

15.3 ± 8.3

17.3 ± 5.6

Entorhinal cortex

27.4 ± 11.3

20.0 ± 8.5

20.8 ± 5.8

38.6 ± 8.6

HS classification ( n )

Severe HS

7

5

5

n.a.

Classical HS

5

6

5

n.a.

CA1 HS

1

2

2

n.a.

CA4 HS

1

0

1

n.a.

p75 ^NTR IR area (μm ² × 10 ² )

Granular layer

3974.2 ± 1425.8

2945.2 ± 1254.1

3064.6 ± 1135.7

1586.7 ± 623.4

Hilus

1961.7 ± 585.5

1708.5 ± 532.3

1721.9 ± 558.6

1115.7 ± 359.1

CA4

2570.1 ± 743.2

1853.3 ± 702.5

2350.2 ± 619.5

1224.4 ± 418.1

CA3

2950.6 ± 693.7

3816.7 ± 1342.0

2756.6 ± 791.6

1964.5 ± 786.6

CA2

4189.7 ± 924.4

3817.4 ± 1085.0

3598.5 ± 726.5

2242.7 ± 910.7

CA1

2941.2 ± 916.4

2660.8 ± 663.0

2583.7 ± 260.7

1572.0 ± 692.3

Prosubiculum

2747.7 ± 896.4

2243.4 ± 568.8

2278.7 ± 529.2

1652.9 ± 810.6

Subiculum

3372.1 ± 1178.8

2549.5 ± 717.1

2342.2 ± 726.0

1275.5 ± 567.6

Parasubiculum

3752.4 ± 1026.5

3349.3 ± 916.4

2704.0 ± 497.6

1397.5 ± 580.2

Entorhinal cortex

3303.6 ± 564.7

3044.3 ± 552.3

3436.0 ± 536.8

1265.0 ± 622.2

TrkB IR area (μm ² × 10 ² )

Granular layer

1970.3 ± 651.6

3883.8 ± 1442.6

4307.5 ± 1039.8

2591.0 ± 539.0

Hilus

1490.4 ± 551.2

2214.4 ± 712.8

2693.6 ± 838.0

1937.9 ± 510.2

CA4

1369.0 ± 602.3

2590.7 ± 1105.6

2861.6 ± 458.0

2911.2 ± 839.6

CA3

1857.9 ± 436.3

2124.1 ± 703.8

3050.8 ± 646.0

3892.2 ± 958.6

CA2

2311.3 ± 700.8

3276.0 ± 1078.4

3182.0 ± 593.3

3732.2 ± 956.4

CA1

1513.3 ± 442.5

1729.8 ± 540.6

1931.2 ± 596.6

2888.2 ± 585.8

Prosubiculum

1454.7 ± 445.4

1427.5 ± 434.1

2224.4 ± 679.7

2694.9 ± 956.7

Subiculum

1649.9 ± 415.1

2776.0 ± 806.4

2843.5 ± 977.7

2531.9 ± 622.9

Parasubiculum

1689.4 ± 425.3

2833.3 ± 499.8

2778.9 ± 412.3

3000.3 ± 1086.8

Entorhinal cortex

1893.1 ± 302.0

2808.3 ± 509.2

2870.6 ± 588.5

2930.0 ± 857.8

TrkA IR area (μm ² × 10 ² )

Granular layer

1757.7 ± 646.3

2155.8 ± 721.3

1444.2 ± 289.9

2181.6 ± 889.4

Hilus

1213.1 ± 549.7

1252.2 ± 479.1

1183.7 ± 378.9

1960.9 ± 716.8

CA4

1441.1 ± 553.3

1441.1 ± 470.7

1322.1 ± 291.9

1802.1 ± 570.2

CA3

1473.9 ± 333.1

1643.2 ± 487.0

1193.3 ± 267.3

2614.6 ± 918.1

CA2

1820.7 ± 587.9

2097.6 ± 607.7

1675.1 ± 421.3

2463.7 ± 768.1

CA1

1157.7 ± 350.1

1042.9 ± 291.3

1179.6 ± 462.2

2169.7 ± 637.2

Prosubiculum

1202.9 ± 345.8

1017.0 ± 380.5

1279.3 ± 295.0

1888.3 ± 566.8

Subiculum

1515.8 ± 360.7

1662.1 ± 456.6

1456.9 ± 375.2

1780.5 ± 555.8

Parasubiculum

1733.4 ± 391.2

1524.4 ± 252.6

1572.3 ± 391.2

1834.7 ± 600.3

Entorhinal cortex

1779.4 ± 641.3

1135.7 ± 429.9

1464.5 ± 295.9

1693.8 ± 383.6

TrkC IR area (μm ² × 10 ² )

Granular layer

1295.3 ± 416.3

1194.4 ± 402.4

1106.0 ± 300.0

1103.5 ± 477.8

Hilus

1120.3 ± 313.4

1114.3 ± 303.8

1076.2 ± 411.7

1427.1 ± 395.4

CA4

1188.5 ± 297.0

1270.0 ± 483.5

1387.8 ± 468.6

1316.9 ± 184.6

CA3

1512.1 ± 425.0

1333.3 ± 787.3

1742.3 ± 608.3

2323.6 ± 772.3

CA2

2076.8 ± 485.9

1630.9 ± 473.3

1808.3 ± 859.2

2012.1 ± 789.9

CA1

1133.3 ± 378.9

1284.6 ± 432.1

1069.6 ± 415.5

1092.8 ± 313.6

Prosubiculum

1200.4 ± 193.7

1069.7 ± 336.3

1083.7 ± 404.3

1117.1 ± 634.2

Subiculum

1261.1 ± 361.2

1158.1 ± 308.1

1172.9 ± 468.8

942.9 ± 154.2

Parasubiculum

1375.7 ± 306.1

1282.1 ± 385.6

1155.6 ± 453.2

1204.2 ± 538.7

Entorhinal cortex

1610.7 ± 438.8

1523.6 ± 522.5

1535.5 ± 598.0

958.1 ± 399.1