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Table 1 Demographic and clinical data

From: Neurotrophin receptors expression in mesial temporal lobe epilepsy with and without psychiatric comorbidities and their relation with seizure type and surgical outcome

 

MTLE

MTLE + D

MTLE + P

Controls

Statistics

Male (n)

8

5

7

4

No difference

Female (n)

6

8

6

6

IPI present (n)

9

8

7

n.a.

No difference

IPI absent (n)

5

5

6

n.a.

Febrile seizure present in IPI (n)

5

3

5

n.a.

No difference

Febrile seizure absent in IPI (n)

4

3

1

n.a.

Febrile seizure unknown (n)

0

2

1

n.a.

Age of first seizure (years)

3.0 ± 2.3

4.3 ± 5.5

6.8 ± 8.4

n.a.

No difference

Age when seizures became recurrent or age of onset (years)

10.2 ± 6.4

13.0 ± 8.1

13.8 ± 8.4

n.a.

No difference

Seizure type: CPS (n)

6

1

4

n.a.

No difference tr

Seizure type: SGS (n)

8

12

9

n.a.

Seizure frequency (monthly)

12.7 ± 10.1

17.2 ± 15.6

11.7 ± 10.1

n.a.

No difference

Right HS (n)

6

7

5

n.a.

No difference

Left HS (n)

6

4

6

n.a.

Bilateral HS (n)

2

2

2

n.a.

Right handedness (n)

12

11

13

n.a.

No difference

Left handedness (n)

1

2

0

n.a.

Bilateral handedness (n)

1

0

0

n.a.

Memory in verbal tasks: average or above (n)

3

7

2

n.a.

No difference

Memory in verbal tasks: below average (n)

11

6

11

n.a.

Memory in non-verbal tasks: average or above (n)

9

7

3

n.a.

No difference tr

Memory in non-verbal tasks: below average (n)

5

6

10

n.a.

Full scale IQ

82.2 ± 7.9

84.3 ± 9.6

77.2 ± 7.3

n.a.

No difference

Years at school

6.2 ± 3.0

5.1 ± 3.6

4.2 ± 2.6

n.a.

No difference

Age at surgery (or at death for controls) (years)

36.1 ± 4.7

37.1 ± 5.4

38.0 ± 6.0

48.1 ± 18.9

No difference

Duration of epilepsy (years)

25.9 ± 6.4

24.1 ± 8.9

24.1 ± 8.6

n.a.

No difference

Collected side: right (n)

7

8

6

6

No difference

Collected side: left (n)

7

5

7

4

Collected side: left (n)

7

9

6

4

 

Surgical outcome: complete remission of seizures (n)

8

2

4

n.a.

Fisher’s Exact Test, p = 0.046: MTLE × MTLE + D

Surgical outcome: only auras and/or fewer seizures (n)

6*

11*

9

n.a.

  1. Values indicated as mean ± std. deviation when applicable. A statistical trend (tr: 0.05 ≤ p ≤ 0.07) was observed suggesting a higher proportion of MTLE + D patients with SGS than MTLE, and a higher proportion of MTLE + P patients with worse performance in non-verbal memory tasks than MTLE.
  2. *: Two patients in MTLE group; one patient in MTLE + D, and four patients in MTLE + P group presented with auras and seizures post-surgery; the remaining had only auras, and the proportion was increased in the MTLE + D group. IPI: initial precipitant injury; CPS: complex partial seizure; SGS: secondarily generalized seizures; HS: hippocampal sclerosis; n.a.: not applicable.