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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Medulloblastoma cerebrospinal fluid reveals metabolites and lipids indicative of hypoxia and cancer-specific RNAs

Fig. 1

Global transcriptomic differences in the CSF of patients with (n = 40) and without (n = 11) MB. A Mapping rate of each CSF sample. B Principal component analysis of CSF samples using the 48 most differentially expressed genes showing clear separation of normal CSF samples from MB CSF samples. C Unsupervised clustering of samples using the 48 most differentially expressed genes showing clear separation of normal CSF samples from MB CSF samples. D Volcano plot showing significantly up- or downregulated genes in CSF. E Volcano plot for differentially expressed circRNAs between normal vs MB CSF samples. F Top 5 circRNAs expression in different subgroups and qRT-PCR validation of circ-463

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Acta Neuropathologica Communications

ISSN: 2051-5960

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