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Table 1 Multivariate regression estimates and associated p-values for normalised S1P in the hippocampus

From: Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer’s disease pathogenesis

Variable Coefficient (β) 1 SE B 2 95% CI p-value
Braak Stage     0.0392
Ctrl vs Braak I/II -0.443 0.35 -1.545, -0.090 0.0290
Ctrl vs Braak III/IV -0.533 0.39 -1.900, -0.283 0.0101
Ctrl vs Braak V/VI -0.393 0.34 -1.400, 0.002 0.0506
APOE Genotype     0.0495
ϵ3/ϵ3 vs ϵ2/ϵ3 0.092 0.39 -0.605, 1.013 0.6090
ϵ3/ϵ3 vs ϵ3/ϵ4 -0.403 0.29 -1.282, -0.074 0.0292
R 2   0.37   
F   3.12   0.025
  1. Reference group for Braak Stage is Control; reference group for APOE Genotype is ϵ3/ϵ3.
  2. 1Standardized regression coefficient; 2Standard error of the coefficient.