Figure 7
From: Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer’s disease pathogenesis
Hippocampal S1P level is related to APOE genotype. (A) S1P/sphingosine ratio in the hippocampus of subjects grouped according to APOE genotype: ϵ2/ϵ3 (n = 5), ϵ3/ϵ3 (n = 16), ϵ3/ϵ4 (n = 11). (B) S1P/sphingosine data after removing subjects with Braak III-VI pathology: ϵ2/ϵ3 (n = 5), ϵ3/ϵ3 (n = 7), ϵ3/ϵ4 (n = 5). Horizontal bars indicate the mean.