Figure 2From: Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer’s disease pathogenesis Ceramide levels in hippocampus and temporal GM remain relatively constant. Levels of the four most abundant ceramide species in (A) hippocampus and (B) temporal GM were determined by LC-MS/MS. Ceramide content is expressed relative to tissue mass. Mean and standard deviation for each of the Braak stage groups are shown. Statistical significance was determined by one-way ANOVA, followed by Dunnett’s post test to compare different Braak groupings to the control group.Back to article page