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Figure 2 | Acta Neuropathologica Communications

Figure 2

From: Distinct patterns of spread of prion infection in brains of mice expressing anchorless or anchored forms of prion protein

Figure 2

Immunohistochemistry for PrPres in brains of tg44 mice following inoculation with different dilutions of RML scrapie. Panels a-e show PrPres staining (brown) using anti-PrP antibody D13. Mice shown in panels a-d had clinical signs consistent with prion infection, whereas mouse in panel e did not have clinical signs and was euthanized at the end of the experiment (668 dpi). The dilution of inoculum and day of euthanasia for each panel are as follows: a: 10-3, 371 dpi; b: 10-4, 382 dpi; c: 10-5, 480 dpi; d: 10-6, 528 dpi; e: 10-7, 668 dpi.

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