Case 2. MRI and macroscopy. (A-B) MRI showing extensive, T2-weighted hyperintense, nodular lesions in the white matter of the left posterior temporal lobe (between white arrows). No change was noted on follow up MRI in 15 months. (C) Coronally sectioned temporal lobe block from autopsy reveals numerous coalescing grey nodules along the junction of cortex and grey matter and in the subjacent white matter, which appear as hypomyelinated nodules by Luxol fast blue – Nissl (bar = 1 cm).