Synapse Loss in db/AD mice. (a) A representative immunoblot of PSD95 expression in brains from older db/AD mice. The immunoblot was visualized with an Odyssey Infrared Imager (LI-COR). Red = PSD95, Green = GAPDH. (b) Analysis of PSD95 expression in the four main genotypes. PSD95 expression was standardized to that of GAPDH in the same lane. PSD95 expression was unaffected by either the db (p > 0.3) or the AD (p > 0.09) genotype.