Whole-forebrain histochemical analysis of Arc::dVenus expression. Experience-dependent dVenus expression in various forebrain regions following structured visual stimulation and NFT labeling (Thiazine Red fluorescence) in the brains of rTg4510 mice . Scale bar = 100 μm. dVenus intensities in individual neurons are presented as medians with interquartile ranges. N = 4 control littermates, n = 5 transgenic mice. P-values for Arc::dVenus expression comparison between rTg4510 mice and control littermates: EPd, P = 0.80 (control: n = 293 neurons; transgenic: 419); CLA, P = 0.77 (control: n = 291 neurons; transgenic: 427); PIR, P = 0.57 (control: n = 776 neurons; transgenic; 604); CA1, P = 0.92 (control: n = 394 neurons; transgenic: 396); VISam2/3, P = 0.08 (control: n = 1298 neurons; transgenic: 519); VISp6, P = 0.18 (control: n = 952 neurons; transgenic: 974); AUD2/3, P = 0.65 (control: n = 1427 neurons; transgenic: 1057); AUD6, P = 0.05 (control: n = 739 neurons; transgenic: 962)). Reference atlas image credit: Allen Institute for Brain Science, Allen Mouse Brain Atlas.