Figure 1From: Increased 5-hydroxymethylcytosine and decreased 5-methylcytosine are indicators of global epigenetic dysregulation in diffuse intrinsic pontine glioma Differential H3K27me3, 5mC and 5hmC immunoreactivity in DIPG and extrapontine GBM. Representative micrographs (400×) of immunoreactivity for Histone 3 Lysine 27 trimethylation (H3K27me3), 5-methylcytosine (5mC), and 5-hydroxymethylcytosine (5hmC) in control brain, pediatric glioblastoma (pGBM), adult glioblastoma (aGBM), and diffuse intrinsic pontine glioma (DIPG).Back to article page