Table 1 IDH1/2 mutations detected and identified* with the IDH1/2 PCR assay
From: A new sensitive PCR assay for one-step detection of 12 IDH1/2 mutations in glioma
Gene | Mutation | Base change | Cosmic ID** |
|---|---|---|---|
IDH1 | Arg132His (R132H)* | 395G > A | COSM28746 |
Arg132Cys (R132C)* | 394C > T | COSM28747 | |
Arg132Ser (R132S) | 394C > A | COSM28748 | |
Arg132Gly (R132G) | 394 C > G | COSM28749 | |
Arg132Leu (R132L) | 395G > T | COSM28750 | |
Arg132Val (R132V) | 394_395 CG > GT | COSM28751 | |
Arg100Gln (R100Q) | 299 G > A | COSM88208 | |
IDH2 | Arg172Lys (R172K)* | 515G > A | COSM33733 |
Arg172Met (R172M) | 515G > T | COSM33732 | |
Arg172Trp (R172W) | 514A > T | COSM34039 | |
Arg172Ser (R172S) | 516G > T | COSM34090 | |
Arg172Gly (R172G) | 514A > G | COSM33731 |