Study A | Study B | Study C | Study D | |
---|---|---|---|---|
Injected activity/dose of [ 18 F]flutemetamol (MBq) | Approximately 185; range, 111 to 197 | Mean 200; range, 178 to 252 | Mean (SD, 178 (3.4); range, 174 to 185 | Mean 176; range, 169 to 184 |
MRI image equipment | 3 T Siemens Trio whole-body scanner (Siemens, Erlangen Germany) equipped with a product 8-channel array coil | Siemens 3 T TRIO (Milwaukee, WI, USA) | 1.5 T Philips MRI scanner Gyroscan Intera CV Nova Dual system (Philips Medical Systems, Best, The Netherlands) | |
PET imaging equipment | Allegro whole-body PET scanner (Philips, Andover, MA, USA) obtained in a single FOV | GE Advance PET scanner (GE Medical Systems, Milwaukee, WI, USA) in 3D modes with a 14.875-cm axial FOV obtained in a single FOV | ECAT EXACT HR + scanner (Siemens-CTI, Knoxville, TN, USA) | |
Reconstruction | Reconstructed by a 3-dimensional row-action maximum likelihood algorithm. Approximate spatial resolution was 6 mm. | Reconstructed to 35 transaxial images of 128 x 128 voxels by a back-projection algorithm using manufacturer-provided software correcting for attenuation, scatter, and dead time. Resolution was approximately 6 mm at full width at half maximum. | Not stated. | Not stated. |