Table 1 Median survival time of the fly lines
From: Oligomer-targeting with a conformational antibody fragment promotes toxicity in Aβ-expressing flies
Expressed Aβ variant | Expressed antibody fragment | ||
|---|---|---|---|
None | B10 | KW1 | |
None | 43 ± 0.1 | 43 ± 0.2 | 42 ± 1.1 |
Aβ(1–42)arc | 7 ± 0.1 | 6 ± 0.3 | 7 ± 0.2 |
Aβ(1–42) | 32 ± 0.3 | 31 ± 0.6 | 32 ± 0.3 |
Aβ(1–40) (line Aβ40) | 43 ± 0.6 | 41 ± 0.9 | 28 ± 1.1 |
Aβ(1–40) (line Aβ40-51D) | 42 ± 1.1 | - | 36 ± 0.8 |
Aβ(1–40) (line Aβ40-29.1) | 39 ± 0.8 | - | 39 ± 0.4 |