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Table 3 Summary of the semiquantitative grading of tau accumulation

From: Tau accumulation in the nucleus accumbens in tangle-predominant dementia

 

Braak stage

No. of cases

Acb

Caudate nucleus

Septal nucleus

CA1

Ent

Temp

TPD

III-IV

7

2.6

0.7

2.2

3

2.57

0.4

Non-demented

I-II

3

0

0

0

0.67

1

0

III

8

1.13

0.25

0.63

1.38

2

1

AD

IV

10

1.2

0.6

1.4

2.67

3

1.4

V

8

0.9

0.9

1.3

2.89

2.9

2.5

VI

4

1.3

1.3

1.7

3

3

3

  1. The numbers indicate averages of the scores in each group. The degree of tau pathology was qualitatively scored as 0: absent 1: low 2: intermediate 3: high.
  2. TPD, Tangle predominant dementia; AD, Alzheimer’s disease; NFT, Neurofibrillary tangles; Acb, nucl. Accumbens; CA1, Hippocampal CA1 region; Ent, Entorhinal cortex; Tmep, Temporal neocortex.